Figure 1 | Scientific Reports

Figure 1

From: Live Intracellular Biorthogonal Imaging by Surface Enhanced Raman Spectroscopy using Alkyne-Silver Nanoparticles Clusters

Figure 1

Cluster’s base structure. The silver-sulfur interaction is exploited to link alkyne-dopamine adducts and DTT molecules, both bearing a free –SH group, on the surface of AgNPs. DTT also provides a second –SH to trigger assembly of nanoparticles into small colloidal clusters. The DTT layer ensures tailoring of nano-sized interparticle gaps where SERS rises up to enhance the Raman detectability of the alkyne-dopamine adducts in the cell-silent window upon inside the cell.

Back to article page