Table 1 Distribution of ferric ion in each organ after single i.v. injection of transferrin into tumor-bearing mice.

From: Transferrin as a thermosensitizer in radiofrequency hyperthermia for cancer treatment

 

Apotransferrin

(μg/g)

Transferrin

(μg/g)

Fold increase

Tumor

13.5 ± 1.34

43.9 ± 9.7

3.25

Liver

74.5 ± 7.5

94.7 ± 8.1

1.27

Lung

28.3 ± 6.1

43.9 ± 17.9

1.55

Kidney

56.9 ± 7.5

41.2 ± 1.7

0.72

Heart

32.2 ± 1.8

70.1 ± 12.3

2.18

Muscle

29.5 ± 4.2

25.7 ± 5.2

0.87

Stomach

27.8 ± 3.8

46.4 ± 14.9

1.67

Brain

22.5 ± 3.7

28.4 ± 3.5

1.26

  1. The ferric ion in each organ of the tumor-bearing mice was quantitated by the ICP-MS method after complete acid lysis of the organs. The values represent the mean ± standard deviation (n = 6).
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