Figure 5 | Scientific Reports

Figure 5

From: Rapid and simple detection of Tamiflu-resistant influenza virus: Development of oseltamivir derivative-based lateral flow biosensor for point-of-care (POC) diagnostics

Figure 5

Sensitivity analysis of Tamiflu resistance detection using OHT-GNPs for colorimetric detection after a 5-min treatment of WT and Tamiflu-resistant viruses. (a) Images of the colorimetric changes and (b) absorption profiles of OHT-GNP solution in the presence of different virus concentrations (i: WT, and ii: Tamiflu-resistant). (c) The ratio of absorbances at 600 nm and 520 nm (Abs600/Abs520) (Abs: absorption) of (b). Circular dots and error bars indicate the averages and standard deviations from three independent experiments, respectively. This graph implies that the color of the OHT-GNP solution gradually changes to purple as the concentration of the Tamiflu-resistant virus increases, but the color of the OHT-GNP solution hardly changes when WT is present (PFU: plaque-forming units).

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