Figure 5
From: Analyzing protein topology based on Laguerre tessellation of a pore-traversing water network
Contributions to the peripheral genus. (A) Axial channel crossing the entire protein. (B) Peripheral passage, or handle, formed by protein loop contacts in the extracellular domain. In both cases, the hole contributing one unit to the genus is encircled in black. The protein is shown in cartoon mode and Laguerre surface; the lipids in (A) are shown in sticks. The structure was taken at 81 ns of the complexed form MD.
