Table 2 50 most IgG-reactive S. aureus antigen by protein immunoarray.
From: Hierarchy of human IgG recognition within the Staphylococcus aureus immunome
No. | Locus Tag | Protein Name/Description | Signal Peptide | Transmembrane |
|---|---|---|---|---|
1 | SAUSA300-0113 | immunoglobulin G binding protein A (SpA) | + | + |
2 | SAUSA300-0398 | superantigen-like protein SSL4 | + | − |
3 | SAUSA300-0403 | superantigen-like protein SSL9 | + | − |
4 | SAUSA300-2366 | gamma-hemolysin component C (hlgC) | + | − |
5 | SAUSA300-2579 | N-acetylmuramoyl-L-alanine amidase domain protein | + | − |
6 | SAUSA300-0883 | MAP domain-containing extracellular adherence protein Eap | + | − |
7 | SAUSA300-2364 | IgG-binding protein SBI (sbi) | + | − |
8 | SAUSA300-1029 | Iron-regulated surface determinant Protein A (IsdA) | + | + |
9 | SAUSA300-1028 | Iron-regulated surface determinant Protein B (IsdB) | + | + |
10 | SAUSA300-1920 | chemotaxis-inhibiting protein CHIPS (chs) | + | − |
11 | SAUSA300-1382 | Panton-Valentine leukocidin, LukS-PV (lukS-PV) | + | − |
12 | SAUSA300-2367 | gamma-hemolysin component B (hlgB) | + | − |
13 | SAUSA300-1768 | leukotoxin LukD (lukD) | + | − |
14 | SAUSA300-1917 | map protein, programmed frameshift (map) | + | − |
15 | SAUSA300-0651 | peptidase M23 | + | − |
16 | SAUSA300-0951 | V8 protease (sspA) [3.4.21.19] | + | − |
17 | SAUSA300-0408 | heme uptake protein | + | − |
18 | SAUSA300-0438 | CHAP domain family | + | − |
19 | SAUSA300-0409 | peroxidase inhibitor | + | + |
20 | SAUSA300-0693 | electron transfer DM13 | + | − |
21 | SAUSA300-0214 | Sugar phosphate isomerase/epimerase PFAM family PF07582 | − | − |
22 | SAUSA300-2506 | immunodominant staphylococcal antigen A precursor (isaA) | + | − |
23 | SAUSA300-1058 | alpha-hemolysin precursor (HLA) | + | − |
24 | SAUSA300-0548-s2 | sdrE protein (sdrE) | + | + |
25 | SAUSA300-0776 | thermonuclease precursor (nuc) [3.1.31.1] | + | + |
26 | SAUSA300-0547-s2 | sdrD protein (sdrD) | + | + |
27 | SAUSA300-2572 | zinc metalloproteinase aureolysin (aur) [3.4.24.29] | + | − |
28 | SAUSA300-0370 | SEP staphylococcal enterotoxin | − | − |
29 | SAUSA300-1030 | iron transport associated domain protein | + | + |
30 | SAUSA300-1476 | acetyl-CoA carboxylase, biotin carboxyl carrier protein (accB) | − | − |
31 | SAUSA300-1922 | staphylokinase precursor (sak) | + | + |
32 | SAUSA300-0862 | glycerophosphoryl diester phosphodiesterase (glpQ) [3.1.4.46] | + | − |
33 | SAUSA300-1055 | fibrinogen-binding protein (efb) | + | − |
34 | SAUSA300-1481 | hypothetical mating channel protein | + | + |
35 | SAUSA300-0955-s1 | autolysin (atl) [3.5.1.28] | + | − |
36 | SAUSA300-0774 | secretory extracellular matrix, plasma binding protein (empbp) | + | − |
37 | SAUSA300-0950 | cysteine protease precursor (sspB) [3.4.22.48] | + | + |
38 | SAUSA300-1381 | Panton-Valentine leukocidin, LukF-PV (lukF-PV) | + | − |
39 | SAUSA300-2441 | fibronectin binding protein A (fnbA) | + | − |
40 | SAUSA300-2136 | iron compound ABC transporter, iron compound-binding protein | + | − |
41 | SAUSA300-2440 | fibronectin binding protein B (fnbB) | + | − |
42 | SAUSA300-0242 | sorbitol dehydrogenase (gutB) [1.1.1.14] | − | − |
43 | SAUSA300-1985 | serine-aspartate repeat family protein, SdrH (sdrH) | + | + |
44 | SAUSA300-0279 | membrane protein YhgE, type VII secretion protein EsaA) | − | + |
45 | SAUSA300-0708 | histidinol-phosphate aminotransferase (hisC) [2.6.1.9] | − | − |
46 | SAUSA300-0399 | superantigen-like protein SSL5 | + | − |
47 | SAUSA300-0955-s2 | autolysin (atl) [3.5.1.28] | + | − |
48 | SAUSA300-0395 | superantigen-like protein SSL1 | + | − |
49 | SAUSA300-1031 | heme ABC transporter permease | − | + |
50 | SAUSA300-1512 | penicillin-binding protein 3 (pbp3) | − | + |
