Table 1 Comparison of baseline risk factors of study subjects stratified by blood pressure (BP) control levels.
All adults with hypertension | Below 2017 ACC/AHA target | Below JNC8 but above 2017 ACC/AHA target | Above JNC8 target | P value | |
|---|---|---|---|---|---|
Number of subjects (%) | 373,800 (100.0%) | 96,317 (25.8%) | 145, 981 (39.0%) | 131, 502 (35.2%) | |
Age, years | 56.8 ± 9.5 (373,800) | 56.6 ± 9.2 (96,317) | 57.1 ± 9.6 (145,981) | 56.7 ± 9.5 (131,502) | 0.275 |
Female sex, % | 42.0% (157,005/373,800) | 46.7% (44,992/96,317) | 41.6% (60,700/145,981) | 39% (51,313/131,502) | <0.001 |
Body mass index, kg/m2 | 24.3 ± 3.0 (373,664) | 23.7 ± 2.9 (96,283) | 24.3 ± 2.9 (145,945) | 24.8 ± 3.0 (131,436) | <0.001 |
Blood pressure | |||||
Baseline SBP, mmHg | 140.4 ± 12.4 (340,776) | 136.2 ± 9.1 (74,832) | 137.5 ± 9.9 (135,669) | 145.9 ± 14.4 (130,275) | <0.001 |
Baseline DBP, mmHg | 87.8 ± 8.1 (340,776) | 85.3 ± 6.4 (74,832) | 85.9 ± 6.8 (135,669) | 91.2 ± 8.9 (130,275) | <0.001 |
Achieved SBP, mmHg | 131.4 ± 17.2 (373,800) | 113.6 ± 8.7 (96,317) | 128.4 ± 8.0 (145,981) | 147.7 ± 14.4 (131,502) | <0.001 |
Achieved DBP, mmHg | 81.7 ± 11.0 (373,800) | 69.5 ± 5.6 (96,317) | 80.3 ± 4.5 (145,981) | 92.3 ± 8.8 (131,502) | <0.001 |
Comorbidities, % | |||||
Diabetes | 6.6% (24,733/373,800) | 6.9% (6,631/96,317) | 5.7% (8,307/145,981) | 7.4% (9,795/131,502) | <0.001 |
Dyslipidemia | 17.5% (65,541/373,800) | 22.0% (21,183/96,317) | 17.7% (25,811/145,981) | 14.1% (18,547/131,502) | <0.001 |
Current smoking | 21.2% (76,062/358,407) | 19.8% (18,392/92,714) | 20.9% (29,257/140,043) | 22.6% (28,413/125,650) | <0.001 |
Malignancy | 4.4% (16,432/373,800) | 6.2% (5,987/96,317) | 4.6% (6,659/145,981) | 2.9% (3,786/131,502) | <0.001 |
Renal disease | 0.5% (2,029/373,800) | 0.7% (666/96,317) | 0.5% (696/145,981) | 0.5% (667/131,502) | <0.001 |
Liver disease | 0.5% (1,731/373,800) | 0.7% (694/96,317) | 0.5% (668/145,981) | 0.3% (369/131,502) | <0.001 |
Chronic pulmonary disease | 26.2% (97,919/373,800) | 33.0% (31,787/96,317) | 27.5% (40,142/145,981) | 19.8% (25,990/131,502) | <0.001 |
Rheumatic disease | 6.5% (24,483/373,800) | 8.7% (8,382/96,317) | 6.7% (9,833/145,981) | 4.8% (6,268/131,502) | <0.001 |
Laboratory findings | |||||
Total cholesterol, mg/dL | 201.5 ± 38.1 (373,323) | 197.3 ± 37.1 (96,180) | 201.3 ± 37.6 (145,816) | 204.9 ± 39.0 (131,327) | <0.001 |
HDL cholesterol, mg/dL | 54.4 ± 28.3 (332,700) | 54.8 ± 27.5 (88,600) | 54.4 ± 28.2 (131,619) | 54.0 ± 29.0 (112,481) | 0.037 |
LDL cholesterol, mg/dL | 117.4 ± 38 (330,722) | 118.4 ± 37.2 (88,224) | 118.2 ± 37.8 (130,835) | 115.7 ± 38.9 (111,663) | <0.001 |
Triglyceride, mg/dL | 145.1 ± 93.6 (332,428) | 134.5 ± 86.4 (88,548) | 144.3 ± 91.8 (131,517) | 154.5 ± 99.9 (112,363) | <0.001 |
Serum creatinine, mg/dL | 1.1 ± 1.3 (332,713) | 1.0 ± 1.1 (88,602) | 1.1 ± 1.3 (131,623) | 1.1 ± 1.4 (112,488) | 0.819 |
