Table 1 Summary of two-way ANOVA statistics examining the influence of two factors, Lung (with four levels: LL_Ant, LL_Post, RL_Ant, RL_Post), Treatment (with two levels: LMS, SAL), and their interaction (Lung*Treatment) (total degrees of freedom = 40) on % Area collagen, % Area ASMA, % Area DC-LAMP stain, the number and size of DC-LAMP positive particles, the nearest neighbour distance (NND) between DC-LAMP positive particles, and the number of Ki67 positive particles. The F ratios and P values are depicted in the factor columns, and the fitted means (SE mean) for each factor level is given in the level columns. For clarity, the latter are only shown where the relevant factor effect is significant.

From: Nebulisation of synthetic lamellar lipids mitigates radiation-induced lung injury in a large animal model

Variable

 

Factor

Levels

Factor

Levels

Interaction

Lung

LL_Ant

LL_Post

RL_Ant

RL_Post

Treatment

LMS

SAL

Lung*Treatment

% Area collagen

F ratio

5.72

3.685 (0.750)

7.787 (0.750)

5.562 (0.750)

6.751 (0.750)

1.51

  

4.53

P

0.002

    

0.227

  

0.008

% Area ASMA

F ratio

1.26

    

28.45

0.1060 (0.0507)

0.4882 (0.0507)

2.58

P

0.303

    

0.000

  

0.067

% Area DC-LAMP stain

F ratio

0.31

    

3.33

  

0.39

P

0.820

    

0.076

  

0.759

Number of DC-Lamp positive particles

F ratio

0.17

    

4.19

61.73 (3.56)

51.43 (3.56)

1.35

P

0.918

    

0.047

  

0.273

Size of DC-LAMP positive particles

F ratio

10.76

2.8953 (0.0174)

2.9649 (0.0174)

2.8327 (0.0174)

2.8599 (0.0174)

0.00

  

1.75

P

0.000

    

0.966

  

0.170

DC-LAMP NND

F ratio

47.92

17.83 (1.95)

8.67 (1.95)

36.25 (1.95)

35.25 (1.95)

0.36

  

5.66

P

0.000

    

0.554

  

0.002

Number of Ki67 positive particles

F ratio

7.75

1.1208 (0.0755)

1.3704 (0.0755)

0.9011 (0.0755)

0.9589 (0.0755)

1.55

  

3.19

P

0.000

    

0.221

  

0.034