Table 3 The Nucleotide and Amino acid mutations among the su-genotype C1, cluster 1, cluster 2 and cluster 3 of sub-genotype C2 in VP1 region.

From: The emerging sub-genotype C2 of CoxsackievirusA10 Associated with Hand, Foot and Mouth Disease extensively circulating in mainland of China

Sub-genotype/ Cluster

Total number of sequences

Nucleotide

Amino acid

Nucleotide

Amino acid

Nucleotide

Amino acid

(68/894)

(23/298)

(813/894)

(271/298)

(847/894)

(283/298)

G → T

G → V

C → G

L

A → G

I → V

C1

14

4(28.57%)*

0*

1(7.14%)*

C2

Cluster-1

16

0*

1(6.25%)*

0*

Cluster-2

115

7(6.09%)*

111(96.52%)*

4(3.48%)*

Cluster-3

107

63(58.88%)*

95(88.79%)*

57(53.27%)*

  1. Note: * indicated the number and proportion of variation about nucleotide or amino acid.