Table 2 Return to initial α-blocker among patients taking a second α-blocker.

From: Prescription pattern of alpha-blockers for management of lower urinary tract symptoms/benign prostatic hyperplasia

Year medication/treatment started

Initiating α-blocker

Third α-blocker

Tamsulosin (n, %)

Alfuzosin (n, %)

Silodosin (n, %)

Doxazosin (n, %)

Terazosin (n, %)

Return rate (n, %)

2002–3

Tamsulosin

40

9.7%

  

131

31.8%

96

23.3%

145

35.2%

Alfuzosin

20

27.0%

  

13

17.6%

24

32.4%

17

23.0%

Silodosin

    

    

Doxazosin

157

27.9%

49

8.7%

  

200

35.5%

157

27.9%

Terazosin

311

37.9%

63

7.7%

  

220

26.8%

227

27.6%

2005–6

Tamsulosin

145

23.7%

  

128

20.9%

117

19.1%

223

36.4%

Alfuzosin

82

52.9%

  

26

16.8%

22

14.2%

25

16.1%

Silodosin

    

    

Doxazosin

149

45.3%

53

16.1%

  

54

16.4%

73

22.2%

Terazosin

189

41.4%

62

13.6%

  

90

19.7%

115

25.2%

2009–10

Tamsulosin

199

22.2%

133

14.9%

151

16.9%

157

17.5%

255

28.5%

Alfuzosin

127

47.0%

21

7.8%

41

15.2%

28

10.4%

53

19.6%

Silodosin

66

51.2%

19

14.7%

17

13.2%

11

8.5%

16

12.4%

Doxazosin

127

42.8%

46

15.5%

29

9.8%

43

14.5%

52

17.5%

Terazosin

151

42.1%

42

11.7%

30

8.4%

54

15.0%

82

22.8%

  1. Data are presented as number of patients (%: Percentage of the total number of third α-blockers of each initiating α-blocker).
  2. Return rate: percentage of the index patients who changed medications and were re-prescribed the first alpha blocker after the first prescription date of each alpha blocker (e.g., Tamsulosin → other alpha blocker → Tamsulosin).