Figure 3 | Scientific Reports

Figure 3

From: TiHo-0906: a new feline mammary cancer cell line with molecular, morphological, and immunocytological characteristics of epithelial to mesenchymal transition

Figure 3

Immunohistochemical characteristics of the tumour. (a) E-cad; tubular epithelial cells strongly positive (arrows). (b) E-cad; polygonal cells in solid anaplastic areas of the tumour are negative. (c) E-cad; well-differentiated spindle cells negative. (d) pan-CK; intense cytoplasmic immunostaining by the neoplastic tubular cells (arrows). (e) pan-CK; polygonal cells moderately positive. (f) pan-CK; spindle cells negative. (g) Vim; moderate immunolabeling of neoplastic tubular epithelial cells (arrows). (h) Vim; intense cytoplasmic immunolabeling of the polygonal cells. (i) Vim; spindle cells moderately positive. (j) CD44; neoplastic tubular cells negative (arrows), polygonal cells moderately to intensely positive (arrowheads). (k) CD44; moderate to intense membrane staining of polygonal cells. (l) CD44; spindle cells moderately positive.

Back to article page