Table 1 Demographic, clinical, and laboratory characteristics at renal biopsy.
P + CTX (n = 85) | P + LEF (n = 73) | P (n = 80) | ACEI/ARB (n = 73) | P value | |
---|---|---|---|---|---|
Age - yr. | 37.2 ± 9.7 | 36.3 ± 12.2 | 36.3 ± 11.6 | 35.9 ± 10.7 | 0.897 |
Female sex - no. (%) | 54(63.5%) | 45(61.6%) | 50(62.5%) | 43(58.9%) | 0.944 |
Duration of disease -mo. | 4(3–7) | 4(3–6) | 4(2–6) | 3(2–4) | 0.002 |
MAP (mmHg) | 95.4 ± 12.5 | 95.5 ± 13.7 | 98.9 ± 15.5 | 97.4 ± 14.9 | 0.361 |
Hypertension (%) | 29(34.1%) | 21(28.8%) | 22(27.5%) | 15(20.5%) | 0.305 |
Gross hematuria (%) | 24(28.6%) | 16(21.9%) | 19(22.5%) | 22(30.1%) | 0.555 |
eGFR(ml/min/1.73 m2)abce | 64.7 ± 35.3 | 81.1 ± 30.4 | 89.3 ± 30.4 | 91.6 ± 29.2 | p < 0.001 |
Cr (umol/L)abc | 123.1 ± 49.3 | 99.0 ± 43.1 | 99.9 ± 43.6 | 86.8 ± 33.8 | p < 0.001 |
UA (mmol/L) | 384.8 ± 113.7 | 355.0 ± 116.8 | 372.3 ± 109.2 | 361.8 ± 105.0 | 0.456 |
Proteinuria (g/d)cef | 1.5(0.9–2.5) | 1.8(0.7–2.9) | 1.2(0.9–2.6) | 0.8(0.4–1.3) | p < 0.001 |
nephrotic range proteinuria%cef | 16.5 | 17.8 | 17.5 | 1.4 | 0.007 |
Hb(g/dL) | 125.9 ± 22.1 | 129.0 ± 21.5 | 132.8 ± 20.8 | 132.0 ± 20.5 | 0.157 |
Alb (g/L)cef | 36.8 ± 6.9 | 37.7 ± 5.8 | 38.2 ± 7.8 | 42.9 ± 5.2 | p < 0.001 |