Figure 4

Arrival times of MF and CF mediated local field potentials evoked by mechanical hand stimulation before and after injury. (A) Identification of the MF onset and the CF peak, based on arrival times (arrows). Stimulus is at 0 ms. (B) MF and CF delays for each array contact were averaged across multiple trials (2–3 trials per day) separately in each day and animal (3 rats indicated by different symbols) and plotted against each other as an x-y chart to show the variation across 31-channels of the recording array. Histograms show day-by-day (color coded) changes in the mean and distribution of the delays. All statistical significances were performed with paired comparisons between pre-injury (control) vs. each day of post-injury. N = 3, Mann-Whitney; *P < 0.01, **P < 0.001, ***P < 0.0001. (C) All histograms from different days are merged into a single plot to demonstrate the trends in MF and CF delays day-by-day.