Table 5 Top 10 results GO analysis for putatively differentially methylated regions (P < 0.0005).

From: Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure

GO Term

Category

Number of genes for GO term

Number of DM genes

P-value

FDR

Vacuolar part

CC

702

18

3.25E-06

0.068772

Vacuolar membrane

CC

596

15

2.83E-05

0.291939

Vacuole

CC

1184

22

4.14E-05

0.291939

Voltage-gated calcium channel activity involved in cardiac muscle cell action potential

MF

5

2

0.000514

1

Transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding

MF

25

3

0.000763

1

L-type voltage-gated calcium channel complex

CC

6

2

0.000768

1

Coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway

MF

6

2

0.000768

1

Melanosome organization

BP

26

3

0.000857

1

Pigment granule organization

BP

27

3

0.000959

1

Lysosomal membrane

CC

283

8

0.001081

1

  1. Columns represent Gene Ontology (GO) term, Category (being: CC: Cellular Component, MF: Molecular Function and BP: Biological Process), the number of genes in the gene set, the number of “differentially methylated” genes (loose P < 0.0005 cut-off), the P-value, and False Discovery Rate (FDR).