Table 6 Top 10 results for pathway analysis for putatively differentially methylated regions (P < 0.0005).

From: Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure

Pathway

Number of genes in pathway

Number of DM genes

P-value

FDR

mTOR signaling pathway

151

6

0.00076536

0.248742101

HTLV-I infection

255

7

0.00239934

0.375649312

Oxytocin signaling pathway

153

5

0.00502011

0.375649312

MAPK signaling pathway

295

7

0.00537556

0.375649312

AGE-RAGE signaling pathway in diabetic complications

99

4

0.00577922

0.375649312

Cholinergic synapse

112

4

0.00889251

0.469555659

Cortisol synthesis and secretion

63

3

0.01080852

0.469555659

Long-term potentiation

67

3

0.0127745

0.469555659

Autophagy - animal

128

4

0.01402011

0.469555659

  1. Columns represent KEGG pathway, the number of genes in a pathway, the number of “differentially methylated” genes (loose P < 0.0005 cut-off), the P-value, and False Discovery Rate (FDR).