Table 6 Top 10 results for pathway analysis for putatively differentially methylated regions (P < 0.0005).
From: Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure
Pathway | Number of genes in pathway | Number of DM genes | P-value | FDR |
---|---|---|---|---|
mTOR signaling pathway | 151 | 6 | 0.00076536 | 0.248742101 |
HTLV-I infection | 255 | 7 | 0.00239934 | 0.375649312 |
Oxytocin signaling pathway | 153 | 5 | 0.00502011 | 0.375649312 |
MAPK signaling pathway | 295 | 7 | 0.00537556 | 0.375649312 |
AGE-RAGE signaling pathway in diabetic complications | 99 | 4 | 0.00577922 | 0.375649312 |
Cholinergic synapse | 112 | 4 | 0.00889251 | 0.469555659 |
Cortisol synthesis and secretion | 63 | 3 | 0.01080852 | 0.469555659 |
Long-term potentiation | 67 | 3 | 0.0127745 | 0.469555659 |
Autophagy - animal | 128 | 4 | 0.01402011 | 0.469555659 |