Figure 3
From: DNA hypermethylation and differential gene expression associated with Klinefelter syndrome
KS are associated with altered expression of autosomal coding genes. (A) Multi-dimensional scaling plot based on the biological coefficient of variation of autosomal coding gene expression data between KS (green), male controls (blue) and female controls (orange). (B) Venn diagram of autosomal coding gene expression data with FDR < 0.05 and absolute log fold change ≥0.3. (C) Volcano plots of FDR against log fold change of differentially expressed autosomal coding genes. Orange dots are differentially expressed autosomal coding genes with FWER < 0.05 and absolute log fold change ≥0.3. Red line represents FWER = 0,05. (D) Manhattan plot of differentially expressed genes between KS and male controls (top) and KS and female controls (bottom). Red line represents FWER < 0.05.
