Table 4 Univariate and multivariate analysis of prognostic parameters of breast cancer death.

From: Ghrelin expression is associated with a favorable outcome in male breast cancer

 

HR (95% CI)

p-value

Univariate analysis

Tumor size

>20 mm vs. ≤20 mm

2.83 (1.44–5.58)

<0.01

Node status

pN1-3 vs. pN0

5.54 (2.30–13.37)

<0.01

Ki67

≥14% vs. <14%

1.40 (0.71–2.60)

0.31

HER2

pos vs. neg

1.41 (0.55–3.65)

0.48

Tumor grade

III vs. I + II

1.49 (0.80–2.78)

0.21

Age

50–69 yrs. vs. <50 or ≥70 yrs.

1.07 (0.56–2.05)

0.84

Ghrelin intensity

0 vs. 1 + 2 + 3

0.39 (0.18–0.88)

0.01

Obestatin intensity

0 vs. 1 + 2 + 3

0.38 (0.11–1.24)

0.11

Multivariate analysis

Tumor size

>20 mm vs. ≤20 mm

1.78 (0.85–3.72)

0.13

Node status

pN1-3 vs. pN0

4.52 (1.82–11.20)

<0.01

Ghrelin intensity

0 vs. 1 + 2 + 3

0.38 (0.17–0.88)

0.02

  1. Hazard ratio (HR) and 95% confidence intervals (CI) obtained from Cox regression models. HER2, human epidermal growth factor receptor 2.