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Figure 1

From: Nystatin-like Pseudonocardia polyene B1, a novel disaccharide-containing antifungal heptaene antibiotic

Figure 1

Polyene macrolides investigated in this study. Nystatin A1, a typical tetraene polyene macrolide produced by Streptomyces noursei; amphotericin B, the most potent polyene macrolide produced by Streptomyces nodosus; nystatin-like Pseudonocardia polyene (NPP) A1, produced by Pseudonocardia autotrophica wild-type; NPP B1, produced by enoyl reductase (ER) domain in module 5 (ER5) inactivation mutant of P. autotrophica.

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