Table 1 RF results of top 5 most important biomarkers (mean decrease in accuracy).

From: Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome

Myocardial TG

Epicardial fat

Pericardial fat

Liver fat

Clinical Data

LV early diastole

Visceral fat

Waist

Waist

Waist

Leptin

Visceral fat

Fasting insulin

Weight

Insulin 1 h

Leptin

HOMA-index

AFABP

AFABP

Fasting insulin

Visceral fat

BMI

Fasting insulin

HOMA-index

Weight

Inflammation-Associated Proteome

FGF 21

TNFSF 14

HGF

CDCP1

LAPTGF-β1

FGF 21

CDCP1

FGF 21

IL 18R1

IL 18R1

TNFSF 14

HGF

HGF

HGF

TRAIL

IL 18R1

CDCP1

IL 6

IL 18R1

IL 6

Lipidome

CE 20:3

CE 20:3

diSM 18:0

TAG 50:1

TAG 56:4

PC 38:3

LPC 18:2

diSM 18:0

PC 38:3

LPC 16:1

PC 38:3

CE 20:3

LPC 18:2

TAG 52:1

LPC 16:0

SM 18:0

CE 16:1

CE 18:0

CE 20:3

TAG 52:1

Metabolome

Glutamate

*PE (16:0/18:1)

*CER (d18:0/16:0)

Glutamate

Glucose

*PI (18:0/20:4)

Glutamate

γ- glutamyl-leucine

*DAG (16:0/18:2)

Glutamate

Glucose

*CER (d18:0/16:0)

*PE (18:0/20:4)

*PE (18:0/20:4)

*PC (18:0/20:4)

*DAG (16:0/18:2)

*PC (16:0/16:1)

*SM (d18:2/16:0, d18:1/16:1)

*SM (d18:2/16:0, d18:1/16:1)

*PE (16:0/18:1)

  1. *DAG (16:0/18:2) – 1-palmitoyl-3-linoleoyl-glycerol (16:0/18:2); *PE (18:0/20:4) – 1-stearoyl-2-arachidonoyl-GPE (18:0/20:4); *PC (16:0/16:1) – 1-palmitoyl-2-palmitoleoyl-GPC (16:0/16:1); *PE (16:0/18:1) – 1-palmitoyl-2-oleoyl-GPE (16:0/18:1); *PI (18:0/20:4) – 1-stearoyl-2-arachidonoyl-GPI (18:0/20:4); ‘SM (d18:2/16:0, d18:1/16:1) – sphingomyelin (d18:2/16:0, d18:1/16:1); *CER (d18:0/16:0) – N-palmitoyl-sphinganine (d18:0/16:0); *PC (18:0/20:4) – 1-stearoyl-2-arachidonoyl-GPC (18:0/20:4).