Figure 7
Wnt signal path annotation results and construction of the regulatory network. (a) Wnt signal pathway51,52,53 (http://www.kegg.jp/kegg/kegg1.html.). Rectangular nodes represent gene products (such as enzymes or some RNA regulator), gene products all belong to the KEGG ONTOLOGY classification system indicated with a blue background (KO) (some have highly similar sequences, and the same pathway proteins with similar functions were classified as a group KO), and gene products on the white background are not part of the KO classification system. Sequencing of the genes annotated in red revealed these non-KO gene products (nodes indicate gene products with the same or similar functions); circular nodes represent compounds (i.e., a substrate or product); a white background with a rounded rectangle indicates another pathway. The arrow shows the direction of the enzyme reaction or the direction of information transfer, the solid line indicates a direct solution, and the dotted line indicates an indirect solution. (b) Wnt signalling pathway regulation network.
