Table 1 Genes differentially expressed in both treatments: QB-90 and IMXQB-90.

From: Quillaja brasiliensis saponin-based nanoparticulate adjuvants are capable of triggering early immune responses

Gene

Gene name

Group

QB-90*

IMXQB-90*

Ccl2

chemokine (C-C motif) ligand 2

Chemokine

17,2

12,5

Ccl3

chemokine (C-C motif) ligand 3

8,7

2,6

Cxcl10

chemokine (C-X-C motif) ligand 10

15,2

9,2

Cxcl11

chemokine (C-X-C motif) ligand 11

Cytokine

69,8

32,4

Csf2

colony stimulating factor 2 (granulocyte-macrophage)

10,3

2,5

Ctla4

cytotoxic T-lymphocyte-associated protein 4

5,1

2,6

Ifng

interferongamma

20,4

11,3

Il10

interleukin 10

3,9

3,9

Il15

interleukin 15

3,4

2,7

Il5

interleukin 5

47,2

100,7

Il6

interleukin 6

22,9

28,3

Fasl

Fas ligand (TNF superfamily, member 6)

7,9

2,5

Fas

Fas (TNF receptor superfamily member 6)

Cytokine receptor

2,3

2,2

Edn1

endothelin 1

Peptidehormone

2,2

2,2

Ptgs2

prostaglandin-endoperoxidesynthase 2

Synthase

16,6

8,2

Socs1

Suppressorofcytokinesignaling 1

Kinasemodulator

9,2

5,1

Stat1

signal transducer and activator of transcription 1

Transcriptionfactor

6,7

3,9

Gzmb

granzyme B

Serine protease

42,5

10,8

Lrp2

low density lipoprotein receptor-related protein 2

Unclassified

−13,1

−2,0

  1. *Refers to fold change variations.