Figure 2 | Scientific Reports

Figure 2

From: Identification and characterization of G-quadruplex formation within the EP0 promoter of pseudorabies virus

Figure 2

Identification of G4 formation in the G-rich region of the EP0 promoter. (A) Single-stranded wild type (WT) and mutated (Mut) DNAs were subjected to denaturing PAGE containing 7 M urea. (B) Single-stranded WT and Mut DNAs were subjected to a native PAGE analysis after annealing in 100 mM K+ buffer. (C) Circular dichroism spectra of WT and Mut ssDNAs. (D) Double-stranded wild type (WT-D) and mutated (Mut-D) DNAs were subjected to native PAGE analyses after annealing or were untreated. The drawings on the right indicate linear and G4-carrying DNAs, respectively.

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