Figure 6

Luciferase reporter assay showing the effects of G4s on the activity of the EP0 and EP0-Mut promoters. (A) Luciferase activities of WT and Mut normalized to Renilla. (B) and (C) The effects of PDS on the luciferase activity of EP0-WT and EP0-Mut normalized to total protein content in the cells. (D) Results of the MTT assay designed to test the cytotoxicity of PDS towards Vero cells. All values are presented as the means ± s.d., n = 3.