Figure 4
Yhhu4952 promotes myelination in the developmental model. (a,b) Representative immunofluorescence staining with MBP (green) and DAPI (blue) of lateral corpus callosum (CC) of the neonatal P10 rats with vehicle or Yhhu4952 treatment. (c–e) Quantification of total MBP (green) fluorescence intensity in CC lateral area. (f–h) Quantification of CC1+ cells per 100 μm2 in CC area. (i,j) Quantification of MBP protein expression levels in CC area. Data are represented as mean ± SEM (n = 4 per group) and analyzed using Student’s t test. *p < 0.05, **p < 0.01 versus vehicle. Full-length blots are presented in Supplementary Fig. 4d.
