Figure 1 | Scientific Reports

Figure 1

From: Identification of RSPO2 Fusion Mutations and Target Therapy Using a Porcupine Inhibitor

Figure 1

RSPO2 fusion genes found in three human tumor tissues. (a) RSPO2 mRNA levels from PDX tumor samples tested by q-PCR assay. (b) RSPO2, RSPO3 and LGR5 mRNA expression in GA007, GA3055, CR3056, GA108, and GA414 samples. (c) EMC2 exon 2-RSPO2 exon 1 fusion in GA007. (d) HNF4 exon 1-RSPO2 exon 2 fusion in GA3055. (e,f) PVT1 exon 1-RSPO2 exon 1 fusion and PVT1 exon 1-RSPO2 exon 3 fusion in CR3056. (g) Nanostring assay of various RSPO2 fusion genes and expression in GA007, GA3055 and CR3056 samples.

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