Figure 1
ATG7 isoforms show differential expression pattern. (A) Schematic representation of ATG7 isoforms. Location of exons lacking in isoforms 2 and 3 is indicated. (B) RNA-seq data from various tissues obtained from GTEX (left panel) and TCGA (right panel) databases were analysed for the expression of ATG7; sample names are indicated on the left, from top to bottom: GTEX: bone marrow, cervix uteri, bladder, fallopian tube, kidney, liver, blood, pituitary, nerve, testis, prostate, small intestine, colon, stomach, oesophagus, pancreas, spleen, lung, thyroid, adrenal gland, brain, salivary gland, skin, breast, vagina, uterus, ovary, heart, blood vessel, muscle, adipose tissue. TCGA: uveal melanoma (UVM), uterine carcinosarcoma (UCS), uterine corpus endometrial carcinoma (UCEC), thymoma (THYM), thyroid carcinoma (THCA), testicular germ cell tumour (TGCT), stomach adenocarcinoma (STAD), skin cutaneous melanoma (SKCM), sarcoma (SARC), rectum adenocarcinoma (READ), prostate adenocarcinoma (PRAD), pheochromocytoma and paraganglioma (PCPG), pancreatic adenocarcinoma (PAAD), ovarian serous cyst adenocarcinoma (OV), mesothelioma (MESO), lung squamous cell carcinoma (LUSC), lung adenocarcinoma (LUAD), liver hepatocellular carcinoma (LIHC), brain lower grade glioma (LGG), acute myeloid leukaemia (AML), kidney renal papillary cell carcinoma (KIRP), kidney clear cell carcinoma (KIRC), head and neck squamous cell carcinoma (HNSC), glioblastoma multiforme (GBM), oesophageal carcinoma (ESCA), diffuse large B-cell lymphoma (DLBC), colon adenocarcinoma (COAD), cholangiocarcinoma (CHOL), cervical and endocervical cancer (CESC), breast invasive cancer (BRCA), bladder urothelial carcinoma (BLCA), adrenocortical cancer (ACC).
