Table 2 Association of inflammatory cytokines with open angle glaucoma, pseudoexfoliation glaucoma, or neovascular glaucoma.

From: High interleukin-8 level in aqueous humor is associated with poor prognosis in eyes with open angle glaucoma and neovascular glaucoma

Cytokine (quintile)

POAG/PEG/NVG

POAG

PEG

NVG

Odds ratio

95% CI

P-value

Odds ratio

95% CI

P-value

Odds ratio

95% CI

P-value

Odds ratio

95% CI

P-value

IL-8

2.21

1.71–2.85

0.000

1.22

0.87–1.73

0.25

2.53

1.74–3.69

0.000

15.9

6.34–39.88

0.000

IL-2

1.79

1.43–2.25

0.000

1.72

1.24–2.39

0.001

1.29

0.96–1.72

0.09

4.34

2.57–7.30

0.000

IL-10

1.79

1.43–2.24

0.000

1.83

1.32–2.55

0.000

1.26

0.94–1.67

0.12

4.36

2.59–7.35

0.000

IL-4

1.67

1.35–2.07

0.000

1.92

1.40–2.64

0.000

1.46

1.12–1.92

0.006

1.78

1.31–2.43

0.000

CCL2

1.66

1.34–2.06

0.000

1.36

1.01–1.84

0.04

1.35

1.02–1.79

0.04

3.87

2.36–6.35

0.000

  1. Logistic regression analyses (POAG/PEG/NVG, left) and multinomial logistic regression analyses (POAG, PEG, or NVG, right) after age adjustment, 95% confidence interval (CI). Primary open angle glaucoma (POAG), pseudoexfoliation glaucoma (PEG), and neovascular glaucoma (NVG). Odds ratio was calculated compared with normal control eyes as base outcome. Control: n = 100, POAG: n = 31, PEG: n = 38, NVG: n = 32.
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