Figure 2

Enhanced mycobacterial control decreases following TB treatment. Samples were collected from volunteers with active TB and LTBI between 1 to 6 months following completion of anti-TB treatment. Whole blood MGIT using BCG Pasteur (A) and M.tb H37Rv (B) was performed. Data meeting the inclusion criteria (duplicate ΔTTP < 6 hours) are shown. For MGIT data, points represent the mean of duplicates; bars represent mean values with SD. A paired t- test was performed to assess net growth before and after treatment. *Represents a p-value of <0.05, **a p-value of <0.01 and ****a p-value of <0.0001. Red circles = active TB and black = LTBI.