Table 2 The functions, locations and abbreviations of DEGs.

From: Analysis of the antimicrobial mechanism of porcine beta defensin 2 against E. coli by electron microscopy and differentially expressed genes

Name

Main functions

Locations

Abbreviations

Transporter

potassium transporting ATPase subunit B

potassium transport, this subunit is responsible for energy coupling to the transport system

integral component of membrane

kdpB

ferrichrome transporter ATP-binding protein FhuC

involved in iron(III) hydroxamate import, responsible for energy coupling to the transport system

peripheral proteins of the cytoplasmic membrane

FhuC

preprotein translocase subunit SecY

the central subunit of the protein translocation channel SecYEG

integral component of membrane

SecY

DL-methionine transporter subunit

involved in methionine import

integral component of membrane

metI

Lipid transporter ATP-binding/permease

involved in lipid A export and for biogenesis of the outer membrane

integral component of membrane

msbA

Phosphate ABC transporter substrate-binding protein

involved in phosphate import

integral component of membrane

pstS

Metabolism

succinyl-CoA synthetase, beta subunit

carbon metabolism, energy metabolism, citric acid cycle(TCA cycle)

in cytoplasm

sucC

trehalose-6-phosphate phosphatase

glucose metabolism, osmotic adaptation

unknown, perhaps in cytoplasm

otsB

alcohol dehydrogenase

energy metabolism, carbon fermentation

in cytoplasm

frmA

S-formylglutathione hydrolase

hydrolyzes S-formylglutathione to glutathione and formate

unknown, perhaps in cytoplasm

frmB/YeiG

LPS core phosphoethanolamine transferase

catalyzes the addition of a diphosphoethanolamine moiety to the outer membrane lipopolysaccharide core

integral component of membrane

eptC

soluble pyridine nucleotide transhydrogenase

pyridine nucleotide-disulfide oxidoreductase family protein, has an impact on the redox balance of cells

in cytoplasm

udhA/sthA

ethanolamine ammonia-lyase, large subunit

intracellular amino acid metabolism

unknown, perhaps in cytoplasm

eutB

chloramphenicol acetyltransferase

transport of small molecules

unknown, perhaps in cytoplasm

cat

2-octaprenyl-6-methoxyphenyl hydroxylase

FAD/NAD(P)-binding protein

unknown, perhaps in cytoplasm

ubiH

DNA transcription and translation

23S rRNA

ribosomal component, protein synthesis

in cytoplasm

23S rRNA

50S ribosomal protein L14

ribosomal proteins, protein synthesis

in the ribosomal

rplN

lysine tRNA synthetase

tRNA synthesis, protein synthesis

in cytoplasm

lysS

histidyl-tRNA synthetase

tRNA synthesis, protein synthesis

in cytoplasm

hisS

10saRNA

transcriptional regulator

in cytoplasm

10SaRNA

lactose operon repressor

transcriptional regulator, repressor of the lactose operon

in cytoplasm

lacI

transcriptional regulator Cbl

HTH-type transcriptional regulator, transcriptional regulator of cysteine biosynthesis

in cytoplasm

cb1

regulatory RNA CsrB

control bacterial gene expression post-transcriptionally

in cytoplasm

CsrB

phosphohistidine phosphatase

catalytic diphosphoric acid reaction

in cytoplasm

sixA

DNA-directed RNA polymerase, beta subunit

transcription

in cytoplasm

rpoB

16S rRNA (cytosine(1402)-N(4)) -methyltransferase

catalyzes the N4-methylation of cytosine in 16sRNA

in cytoplasm

rsmH

coding tRNA between 16sRNA and 23sRNA

coding tRNA

in cytoplasm

tRNA

Protein besides sequences

phospholipase D family protein

related to the metabolism of phospholipids

unknown, perhaps in cytoplasm

phD

methylenetetrahydrofolate reductase

involved in the tetrahydrofolate pathway interconversion, which is part of one-carbon metabolism

in cytoplasm

metF

catalase/peroxidase HPI

bifunctional enzyme with both catalase and broad-spectrum peroxidase activity

unknown, perhaps in cytoplasm

katG

protein CsiD

combined with Fe2+

unknown, perhaps in cytoplasm

csiD

SsrA-binding protein

binds to tmRNA, and required for rescue of stalled ribosomes

in cytoplasm

smpB

protein syd

interacts with the SecY protein in vivo

in membrane

syd

glycerate kinase 2

glucose metabolism

unknown, perhaps in cytoplasm

gk2

bacterial regulatory helix-turn-helix, lysR family protein

combine with DNA, regulated transcription

in cytoplasm

lysR

TonB-dependent siderophore receptor family protein

transport, related to siderophore transport

in outer membrane

TonB

serine protease sat autotransporter

has serine-type endopeptidase activity

in outer membrane

sat

citrate lyase acyl carrier protein

covalent carrier of the coenzyme of citrate lyase

in cytoplasm

citD

citrate (pro-3S)-lyase ligase

ligase

unknown, perhaps in cytoplasm

citC