Table 1 Changes in protein secretion in TIMP3 expressing cells.
Protein name | Gene | ID | Ratio | p-value | pept |
|---|---|---|---|---|---|
Selected soluble proteins increased in the conditioned medium of TIMP3 expressing cells | |||||
Metalloproteinase inhibitor 3 | TIMP3 | P35625 | 793.91 | 1.65E-05 | 17 |
Pentraxin-related protein PTX3 | PTX3 | P26022 | 9.55 | 1.41E-04 | 18 |
Metalloproteinase inhibitor 1 | TIMP-1 | P01033 | 4.51 | 1.77E-02 | 13 |
Macrophage migration inhibitory factor | MIF | P14174 | 2.82 | 1.02E-02 | 6 |
Selected soluble proteins decreased in the conditioned medium of TIMP3 expressing cells | |||||
Galectin-3-binding protein | LGALS3BP | Q08380 | 0.18 | 1,99E-02 | 34 |
Laminin subunit alpha-4 | LAMA4 | LAMA4 | 0.21 | 2.55E-02 | 43 |
Plasma alpha-L-fucosidase | FUCA2 | Q9BTY2 | 0.24 | 4.85E-02 | 22 |
Selected membrane proteins showing reduced shedding in TIMP3 expressing cells | |||||
Ephrin-B2 | EFNB2 | P52799 | 0.22 | 2.18E-02 | 5 |
Protocadherin-9 | PCDH9 | Q9HC56 | 0.29 | 8.61E-03 | 14 |
Proprotein convertase subtilisin/kexin type-5 | PCSK5 | Q92824 | 0.31 | 1.37E-02 | 19 |
Transforming growth factor beta receptor type 3 | TGFBR3 | Q03167 | 0.36 | 2.73E-02 | 8 |
Amyloid-like protein 2 | APLP2 | Q06481 | 0.37 | 1.11E-03 | 22 |
Amyloid beta A4 protein | APP | P05067 | 0.37 | 6.66E-03 | 29 |
Ephrin type-A receptor 4 | EPHA4 | P54764 | 0.44 | 3.89E-02 | 7 |
Neuropilin-1 | NRP1 | O14786 | 0.49 | 4.16E-04 | 15 |
Receptor-type tyrosine-protein phosphatase kappa | PTPRK | Q15262 | 0.51 | 2.58E-02 | 13 |
Prostaglandin F2 receptor negative regulator | PTGFRN | Q9P2B2 | 0.54 | 6.15E-03 | 13 |
Cell adhesion molecule 1 | CADM1 | Q9BY67 | 0.65 | 2.86E-02 | 8 |
Anthrax toxin receptor 1 | ANTXR1 | Q9H6X2 | 0.71 | 8.25E-03 | 3 |
Neogenin | NEO1 | Q92859 | 0.75 | 5.00E-03 | 20 |
