Table 2 Change in biomarker levels for participants out-of-range at baseline.

From: Longitudinal analysis of biomarker data from a personalized nutrition platform in healthy subjects

Biomarker

Baseline median (IQR)

Follow-up median (IQR)

P-value

Sample size

Out-of-range threshold

Vitamin Da

23.7 (6.05)

32.4 (15)

<0.001

383

<30

LDL

149 (27)

139 (41.5)

<0.001

303

>130

Creatine kinase

353 (213.5)

241 (253)

<0.001

227

>230

Glucose

105 (7)

97 (14)

<0.001

77

>100

HDL

42.9 (8)

45 (11.5)

<0.001

215

<50

Cholesterol

221 (33)

217 (47)

<0.001

349

>200

ALT

43 (20.5)

30 (18.5)

<0.001

59

>46(M); >29(F)

Triglycerides

191 (58.75)

144.5 (108.8)

<0.001

88

>150

Cortisol

24.3 (3.7)

19.9 (9)

<0.001

51

>22

Ferritin

8 (4.5)

20.5 (22.5)

<0.001

30

<20(M); <10(F)

hsCRP

4.9 (3.16)

2.5 (4.4)

<0.001

55

>3

AST

51 (13)

30 (12)

<0.001

29

>40

Testosteroneb

219 (62)

406 (337)

<0.001

25

<250(M); <0(F)

Eosinophils

267.5 (103.5)

234 (131.8)

<0.001

40

>200

Mean corpuscular hemoglobin concentration

31.1 (0.95)

32 (2.8)

0.066

36

<32

Sex hormone binding globulin

64 (38)

64 (34)

0.132

325

>40

Free testosteroneb

9.9 (4.4)

10 (4)

0.161

296

<46(M); <0(F)

  1. aP-values for vitamin D were calculated after an adjustment of 2.5 mg/dL down for tests taken during the summer (see Methods).
  2. bAnalyses were stratified by sex for testosterone and free testosterone, but an insufficient amount of females were out-of-range for either marker in our dataset. Results shown for these two markers are based on males only.
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