Table 4 Mood and sleepiness ratings (Means (±Standard Deviations)) in patients vs. healthy controls (left part) and responding vs. non-responding patients (right part) at baseline and after partial sleep deprivation (PSD).

From: Changes in brain arousal (EEG-vigilance) after therapeutic sleep deprivation in depressive patients and healthy controls

 

Patients vs. Controls

N

mean (s.d.)

mean (s.d.)

Post-hoc Tests

Depression Severity (HDRSBech)

Baseline

27/16

7.96 (±2.244)

0.50 (±0.816)

t = 15.622; p < 0.001

After PSD

27/0

3.48 (±2.44)

Sleepiness (SSS) before EEG

Baseline

26/16

3.73 (±1.251)

1.69 (±0.479)

t = 7.486; p < 0.001

After PSD

27/16

3.56 (±1.649)

2.69 (±1.250)

t = 1.816; p = 0.077

Responder vs. Non-Responder

Depression Severity (HDRSBech)

Baseline

17/10

8.41 (±2.033)

7.20 (±2.486)

t = 1.378; p = 0.180

After PSD

17/10

2.06 (±1.435)

5.90 (±2.644)

t = −4.923; p < 0.001

Sleepiness (SSS) before EEG

Baseline

16/10

3.88 (±1.204)

3.50 (±1.354)

t = 0.737; p = 0.468

After PSD

17/10

3.18 (±1.667)

4.20 (±1.476)

t = −1.604; p = 0.121

  1. Annotations: HDRSBech = Hamilton Depression Rating Scale Score according to Bech et al.22; SSS = Stanford Sleepiness Scale; s.d. = standard deviation.