Figure 5

B cells in AL periprosthetic tissues and OA synovial membrane do not express TH, ADRA1, ADRA2A, ADRB2, NPY or Y1R. The expression of TH, ADRB2, ADRA1 and ADRA2A (a), and the expression of NPY and Y1R (b) in B cells (CD20+) was evaluated in periprosthetic tissues from AL patients and in synovial tissues from OA patients through double immunohistochemistry staining. White arrows indicate B cells and white arrowheads highlight positive staining for TH, ADRA1, ADRA2A, ADRB2 and Y1R in cells other than B cells (positive control). Scale bar = 20 μm.