Figure 5
From: Tracking Tumor Colonization in Xenograft Mouse Models Using Accelerator Mass Spectrometry
Tumorigenic and 14C activity in lung and bone metastasis. (A) Lung metastases of differing tumor burden 7-week following PC3 intracardiac injection from 4 mice and (B) quantification of colonized cells from AMS analysis of 14C signal in tissue DNA. (C) X-ray images of femurs from 4 animals 7-week post injection following PC3 intracardiac injection. Red arrows denote sites of osteolytic activity induced by cancer cells and (D) associated quantities of colonized cells in each femur.
