Table 3 The description of the 13 circulating tumor cell positive cases identified by immunocytochemical (ICC) staining, and its comparison with immunofluorescence (IF) staining results.
Sample ID | Sample description | IHC | IF | ||||||
|---|---|---|---|---|---|---|---|---|---|
KAIST ID | SMC ID | Sex | Stage (TNM) | Metastasis | Sample volume (ml) | CTC number | Marker positivity | CTC Number (/5 ml) | EpCAM positivity |
RCC1 | RCC-013 | M | cT3N1M0 | Lymph node | 3 | 1 | CK+ | 0 | N/A |
RCC2 | RCC-014 | M | cT3N0M0 | — | 1 | 1 | EpCAM+ | 0 | N/A |
RCC3 | RCC-016 | M | c T3N0M0 | — | 0.5 | 1 | CK+ | 4 | Negative |
RCC4 | RCC-020 | F | cT4N0M1 | Rt.Adrenal,lung | 1 | 5 | CD10− | 0 | N/A |
RCC4-2 | RCC-020-3 | F | cT4N0M1 | Rt.Adrenal,lung,lympha | 3 | 1 | EpCAM+ | 2 | Positive |
RCC5 | RCC-025-2 | M | cT3aN0M0 | — | 1 | 3 | CK+/EpCAM+ | 1 | Positive |
RCC6 | RCC-030-3 | F | cT3aN1M1 | pelvis, right hepatic lobe, lymphadenopathy | 1 | 1 | EpCAM+ | 2 | Positive |
RCC7 | RCC-039-1 | M | cT3aN0M0 | — | 2 | 1 | CK− | 1 | Positive |
RCC8 | RCC-043-3 | M | cT3bN0M0 | — | 0.5 | 3 | CK− | 7 | Negative |
RCC9 | RCC-046-2 | F | cT1bN0M1 | Several nodule, left lung, R/O Bladder | 0.5 | 3 | CD10− | 1 | Positive |
RCC10 | RCC-047-3 | F | cT3aN0M1 | lung meta | 3 | 1 | CD10+ | 1 | Positive |
RCC11 | RCC-048-1 | M | c T4aN1M0 | 3 | 4 | EpCAM+ | 0 | N/A | |
RCC12 | RCC-049-2 | M | cT3N0M0 | 3 | 1 | CK− | 0 | N/A | |
RCC13 | RCC-029-4 | M | cT4N0M1 | Pulmonary | 3 | 0 | EpCAM+ non-epithelial | 0 | N/A |
