Table 1 Vigilance states under T20 conditions (% [mean ± SEM]).

From: Effects of circadian misalignment on sleep in mice

  

20-h

10-h Dark

10-h Light

LD Ratios

P (LD)

W

1st T20

47.5 ± 1.4

61.9 ± 1.5

33.0 ± 2.4

0.54 ± 0.04

0.002

4th T20

47.5 ± 1.4

43.9 ± 2.1

51.1 ± 2.6

1.17 ± 0.09

0.13

7th T20

50.5 ± 0.4

66.9 ± 2.1

34.1 ± 1.8

0.51 ± 0.04

0.001

P (T20)

0.14

<0.0001

0.0004

 

0.006

NREMS

1st T20

44.3 ± 1.4

34.1 ± 1.4

54.5 ± 2.3

1.61 ± 0.09

0.001

4th T20

44.0 ± 1.0

45.9 ± 1.8

42.0 ± 1.8

0.92 ± 0.06

0.26

7th T20

41.8 ± 1.1

29.9 ± 1.7

53.7 ± 2.6

1.83 ± 0.17

0.003

P (T20)

0.27

<0.0001

0.0055

 

0.007

REMS

1st T20

8.2 ± 0.5

4.0 ± 0.6

12.4 ± 0.7

3.40 ± 0.55

0.002

4th T20

8.5 ± 0.7

10.2 ± 0.9

6.9 ± 1.0

0.69 ± 0.12

0.058

7th T20

7.7 ± 0.9

3.2 ± 0.8

12.2 ± 1.2

6.27 ± 2.54

0.01

P (T20)

0.14

<0.0001

0.0003

 

0.009

  1. Percentage of wakefulness, non-rapid eye movement sleep (NREMS) and rapid eye movement sleep (REMS) (% of total recording time), and Light/Dark (L/D) ratios (amount of vigilance state spent in the 10-h light phase/10-h dark phase) (B6: n = 5). Statistics are indicated by P values for the ‘T20 cycle effect’ (1-way ANOVA), interaction ‘T20 cycle x Phase’ (2-way ANOVA), and for the Light-Dark difference (paired t-tests).