Table 1 Variables associated with baseline miR-1254.
Overall (n = 70) | Lower third (n = 23) | Middle third (n = 23) | Upper third (n = 24) | P-value | |
|---|---|---|---|---|---|
Age, years | 60 (49–68) | 63 (49–71) | 54 (48–60) | 61 (50–68) | 0.101 |
Male sex | 50 (71.4) | 18 (78.3) | 15 (65.2) | 17 (70.8) | 0.641 |
Medical history | |||||
Arterial hypertension | 38 (54.3) | 11 (47.8) | 12 (52.2) | 15 (62.5) | 0.583 |
Diabetes mellitus | 16 (22.9) | 4 (17.4) | 5 (21.7) | 7 (29.2) | 0.681 |
Dyslipidemia | 30 (42.9) | 10 (43.5) | 8 (34.8) | 12 (50.0) | 0.572 |
Smoker | 45 (64.3) | 14 (60.9) | 17 (73.9) | 14 (58.3) | 0.493 |
Prior IHD | 4 (5.7) | 3 (13.0) | 1 (4.4) | 0 | 0.120 |
Anterior infarction | 33 (47.1) | 12 (52.2) | 11 (47.8) | 10 (41.7) | 0.768 |
Grace score | 133 (110–155) | 133 (99–151) | 126 (99–150) | 140 (127–159) | 0.330 |
TIMI risk score | 2 (1–4) | 2 (1–4) | 2 (1–3) | 3 (1–4) | 0.504 |
Killip-kimbal class ≥ II | 13 (18.6) | 4 (17.4) | 5 (21.7) | 4 (16.7) | 0.930 |
Time from chest pain onset to reperfusion | 266 (150–390) | 272 (106–420) | 270 (180–329) | 229 (150–405) | 0.991 |
Laboratory values | |||||
Peak hs-cTnT, ng/ml | 2794 (1589–4943) | 2781 (1105–3675) | 3883 (2279–7120) | 2499 (1434–3355) | 0.091 |
NT-proBNP, pg/ml | 207 (67–501) | 285 (52–744) | 221 (131–390) | 144 (56–403) | 0.603 |
Treatment at discharge | |||||
ACEI/ARB | 58 (82.9) | 21 (91.3) | 19 (82.6) | 18 (75.0) | 0.359 |
Betablockers | 54 (77.1) | 21 (91.3) | 15 (65.2) | 18 (75.0) | 0.114 |
Aldosterone receptor blockers | 11 (15.7) | 5 (21.7) | 3 (13.0) | 3 (12.5) | 0.711 |
Loop diuretics | 5 (7.1) | 2 (8.7) | 1 (4.4) | 2 (8.3) | 1.000 |
Statins | 63 (90.0) | 22 (95.7) | 20 (87.0) | 21 (87.5) | 0.686 |
