Figure 3 | Scientific Reports

Figure 3

From: Sodium tanshinone IIA sulfonate protects ARPE-19 cells against oxidative stress by inhibiting autophagy and apoptosis

Figure 3

STS inhibits autophagy in ARPE-19 cells under oxidative stress. (a) The protein expression levels of LC3-I, LC3-II and p62 were detected by WB and representative protein gel blots are shown. Actin was utilized as a loading control. (b–e) The accompanied histogram of densitometric quantification of LC3-I, LC3-II, LC3-II/-I and p62. Untreated cells were used as a positive control. Experiments in each group were repeated 3 times. Data were analyzed using one-way ANOVA and differences between means were considered statistically significant when P < 0.05, Bonferroni correction of P-value was applied in multiple comparison. The statistical results showed that the comparison among groups was statistically significant.

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