Figure 2
From: Antagonistic and cooperative AGO2-PUM interactions in regulating mRNAs
PUM and AGO2 occupy similar transcript populations, and AGO2 binding is affected by PUM presence on the same UTR. (A) Schematic of potential interactions between AGO2 and the PUM proteins. (B) Number of 3′UTRs bound by any combination of PUM1 (light blue), PUM2 (dark blue), and AGO2 (red). (C) Cumulative distribution plot of minimum log fold change for AGO2 peaks on 3′UTRs with and without Pumilio proteins. (D) Cumulative distribution plot of maximum log fold change for AGO2 peaks on 3′UTRs with and without Pumilio proteins.
