Figure 7
Modulation of inhibited T cell pathways improves host survival. (a) Parasitemia from N67-infected mice untreated or treated with anti-OX40 monoclonal antibody. (b) Host survival curves from N67-infected mice untreated or treated with anti-OX40 monoclonal antibody. (c,d) Parasitemia and host survival from N67-infected mice untreated or treated with anti-CD28 monoclonal antibody. (e,f) Parasitemia and host survival from N67-infected mice untreated or treated with IFN-γ. Significance was tested using Whitney-Mann U test; **p < 0.01; ***p < 0.001. The experiments were independently repeated once with almost the same results.
