Figure 1
From: Appreciation of different styles of humor: An fMRI study

Simple effects of the differential neural mechanisms related to self-directed humor. (Top) Stronger responses to self-defeating humor (SD) than to self-enhancing humor (SE) in the left temporal pole, bilateral midbrain, and right nucleus accumbens (NAc). (Bottom) Parameter estimates (SPM betas) are plotted for these four regions. Standard error of the mean (SEM) bars are shown.