Figure 2
From: SB772077B, A New Rho Kinase Inhibitor Enhances Aqueous Humour Outflow Facility in Human Eyes
Tracer-decorated human aqueous outflow pattern. Frontal sections of anterior segments showing tracer distribution in (A) vehicle control, (B) SB77 (50 µM) treated eyes. Tracer distribution was more uniform, intense and widely spread all over the meshwork and also in the inner wall of SC in SB77-treated eyes as compared to vehicle-treated eyes. (C) Measurement of TM thickness in tracer decorated region. A marginal 11.2% increase in TM thickness was observed in SB77-treated eyes as compared to vehicle-treated eyes (SB77-treated eyes: 129.29 ± 14.3 µm, vehicle control eyes: 116.09 ± 16.7 µm; n = 3; p = 0.354; unpaired t-test). TM-Trabecular meshwork; SC-Schlemm’s canal and S-Sclera.
