Table 1 Study population characteristics.

From: Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases

 

HC (n = 26)

AS (n = 52)

PSA (n = 16)

RA (n = 18)

age, years (median and range)

40.1 [26;64]

41.0 [23;73]

47.9 [26;71]

53.6 [22;84]

male/female, no.

16/10

32/20

9/7

4/14

HLA-B27 positive, %

na

86.7

50.0

na

RF positive, %

na

na

na

75.0

anti-CCP positive, %

na

na

na

86.7*

BASDAI (SD)

na

4.6 (2.5)+

na

na

DAS28 CRP (SD)

na

na

na

2.7 (1.3)^

CRP, mg/L (SD)

na

18.4(26.9)

17.1 (27.5)

7.5 (9.9)

Treatment

anti-TNF, no.

na

11/52

1/16

0/18

DMARD, no.

na

10/52

13/16

18/18

Steroid, no.

na

0/52

0/16

0/18

Comorbidities

na

 

na

na

Uveitis, no.

 

13/52

  

Psoriasis, no.

 

4/52

  

IBD (UC/CD), no.

 

6/52

  
  1. HLA-B27 (human leucocyte antigen-B27), RF (rheumatoid factor), anti-CCP (anti-cyclic citrullinated peptide), BASDAI (Bath Ankylosing Spondylitis Disease Activity Index), DAS28 CRP (Disease Activity Score 28 CRP), CRP (c-reactive protein), DMARD (Disease-modifying antirheumatic drug), IBD (inflammatory bowel disease), UC (ulcerative colitis), CD (Crohn’s disease).
  2. Data available for 44 AS and 4 PSA patients.
  3. Data available for 16 RA patients.
  4. *Data available for 15 RA patients.
  5. +Data available for 45 AS patients.
  6. ^Data available for 14 RA patients.
  7. Data available for 38 AS, 15 PSA and 17 RA patients.