Figure 1
From: The roles of IL-17C in T cell-dependent and -independent inflammatory diseases

Generation of Il17c−/− mice. (a) IL-17C gene targeting strategy. The region of the Il17c gene containing from exon 1 to exon 3 was replaced with a cassette containing a neomycin resistance gene (Neor), flanked by loxP sequences. (b) Expression of Il17c mRNA in various tissues from wild-type (n = 3) and Il17c−/− (n = 3) mice, determined by qPCR. The data show the mean + SEM.