Figure 1

Mouse body weight, composition, cumulative food intake and cecal content (n = 12). (A) Body weight accumulation of the high fat diet (HFD) fed mice differed significantly from those of the HFD where 10% of the carbohydrate by weight (5% corn starch, 5% cellulose) was replaced by the following dietary fibers: beta glucan (HFD + bglucan), apple pectin (HFD + pectin), inulin (HFD + inulin), inulin acetate ester (HFD + inul A), inulin propionate ester (HFD + inul P), inulin butyrate ester (HFD + inul B), inulin propionate and butyrate ester, 5% each (HFD + inul PB) and low fat diet (LFD) fed mice from 2 weeks onwards until the end of the experiment. (B) Body weight of HFD fed mice at week 8 was significantly greater than mice consuming HFD + DF or LFD. Bodyweight of mice at week 8 fed HFD + DF was closer to that of LFD fed mice. (C) The increase in body weight seen in (A,B) is attributed to fat mass, which was increased in the HFD fed mice, while lean mass did not significantly differ with the dietary interventions as measured in mice at week 8. (D) Cumulative food intake measured over the course of the study did not differ in mice receiving either a HFD or HFD + DF. Mice consuming LFD consumed significantly more food. (E) Liver fat (F) Cecal content. Significant (p < 0.05) differences assessed by ANOVA with Fisher’s correction are indicated using lower case letters to distinguish differences between the diets.