Figure 5 | Scientific Reports

Figure 5

From: Dietary fibers inhibit obesity in mice, but host responses in the cecum and liver appear unrelated to fiber-specific changes in cecal bacterial taxonomic composition

Figure 5

Altered ontologies and pathways associated with known genes showing 1.5 fold differences (P < 0.01) in expression in cecum and liver of mice fed a high fat diet (HFD) where 10% of the carbohydrate by weight (5% corn starch, 5% cellulose) was replaced by inulin (HFD + I), inulin propionate and butyrate ester, 5% each (Inulin PB) and low fat diet (LFD) relative to HFD fed mice. The networks are organized into significantly enriched GO categories. (A) Heat map illustrating up and down regulated genes. Cytoscape networks of up-regulated (B) and down-regulated genes in cecum (C) and liver (D). (E) Integrated analysis illustrating up- and down-regulated genes indicated by yellow and blue lines respectively in cecum and liver. Details of gene list shown in Supplementary File S8.

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