Figure 3
From: Unravelling the Role of O-glycans in Influenza A Virus Infection
NMR spectra of influenza A viruses binding to mono-sialylated Galβ(1,3)GalNAc O-glycoforms: 1H NMR spectrum of an equimolar mixture of 3- and 6-Galβ(1,3)GalNAc (a) and STD NMR spectra of 6-sialyl Galβ(1,3)GalNAc (b), 3-sialyl Galβ(1,3)GalNAc (c) and an equimolar mixture of 3- and 6-sialyl Galβ(1,3)GalNAc (d), in complex with H1N1sea, H1N1pdm, H3N2 and H5Vn-VLP. The methyl protons of the acetamido groups of Neu5Ac and GalNAc are shown. For proposed binding epitope maps for sialyl-Galβ(1,3)GalNAc fragments see Supplementary Fig. 7.
