Figure 8
From: Unravelling the Role of O-glycans in Influenza A Virus Infection
Identification of an EQTKLY motif in Highly Pathogenic Avian Influenza (HPAI) strains. Multiple protein sequence alignment of the region containing the crucial GalNAc-binding amino acid residues Lys-193 and Leu-194 (H3 numbering) (★) of several HPAI strains. The two residues can be found within a sequence motif consisting of six amino acids EQTKLY (shown in bold) being highly conserved in all HPAI strains used in this alignment (see Supplementary Fig. 13 for the entire sequence alignment). This sequence motif is not conserved in the human IAV strains H1N1pdm, H1N1sea and H3N2 (alignment not shown).
