Table 2 Therapeutic Effects and Laboratory Data in the Rat Thromboembolic Ischemic Model.

From: Uric acid enhances alteplase-mediated thrombolysis as an antioxidant

 

Control

Alteplase

UA–alteplase combination

n (%)

n (%)

n (%)

Total number of rats

14 (100)

10 (100)

9 (100)

Rats that expired

7 (50)

3 (30)

2 (22)

Haemorrhagic transformation

0 (0)

2 (20)

0 (0)

Blood test data

AST (U/L)

151.9 ± 28.6

169.4 ± 37.5

165.9 ± 61.2

ALT (U/L)

38.1 ± 10.9

40.3 ± 9.0

38.4 ± 12.6

BUN (mg/dl)

13.5 ± 2.4

14.7 ± 1.9

14.6 ± 2.6

Cr (mg/dl)

0.17 ± 0.08

0.19 ± 0.07

0.16 ± 0.05

  1. Blood test data are shown as the mean ± standard deviation.
  2. UA, uric acid; BUN, blood urea nitrogen; Cr, creatinine; AST, aspartate transaminase; ALT, alanine transaminase.