Figure 6
Shared genetic factors among diseases linked to multimorbidity. (A) Matrix depicting pairs of central (blue) and common (green) diseases, and instances with a significant number of shared genetic variants relative to random GWASs (numbers of variants are shown). The corresponding RRs are shown for instances linking central diseases. (B) Distribution of shared genetic variants (also considering those in linkage disequilibrium) among 100 random sets of 31 variants and observed value of shared signals between “Nutritional anemias” and “Diseases of the nervous system”. The y- and x-axes depict the probability and number of shared variants, respectively; red arrows indicate the value observed.
