Figure 4

Bacterial taxa associated with offspring weight gain. (A) Pearson’s correlations of f_Lachnospiraceae, f_Clostridiaceae, g_Coprococcus, g_Adlercreutzia and f_Lactococcus with weight gain over the diet intervention period irrespective of sex of the offspring. Correlation co-efficients and p-values for linear regressions were calculated using Pearson’s correlation. (B) Microbial OTU abundance showing sexually dimorphic expression in male and female offspring when fed postnatal HFD. Data are expressed as means ± SD. Statistical differences between groups were determined using a 2-way ANOVA to examine the effects of maternal HFD and offspring sex.